The results of a study presented on April 29 at the Experimental Biology 2007 meeting in Washington, DC indicate that a compound found in green tea may have preventive and therapeutic benefits for rheumatoid arthritis. Rheumatoid arthritis is an autoimmune disease characterized by inflammation, pain swelling, and gradual erosion of bone and cartilage.
Salah-uddin Ahmed, PhD and colleagues with the University of Michigan Health System incubated cultured synovial fibroblasts from the lining of the joint capsules of rheumatoid arthritis patients with epigallocatechin-3-gallate (EGCG) from green tea. These cells, as well as fibroblast cultures not treated with EGCG, were subsequently stimulated with interleukin-1beta, a pro-inflammatory cytokine produced by the immune system that is involved in the joint destruction experienced by people with the disease. Read more...
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